
Meet the Doctor
Yessar Hussain, MD
Dr. Hussain earned his medical degree at the University of Baghdad College of Medicine in Baghdad, Iraq. He completed his neurology residency at the State University of New York. He finished his fellowship in neuromuscular medicine, electromyography (EMG), and pathology at Washington University School of Medicine at Barnes-Jewish Hospital in St. Louis, MO, one of the leading academic centers in the nation for neuromuscular medicine training.
Dr. Hussain is board certified in neurology, neuromuscular medicine, electrodiagnostic medicine, and clinical neuromuscular pathology.
Dr. Hussain is a board member of the Texas Neurological Society, as well as a member of the American Academy of Neurology and the American Association of Neuromuscular and Electrodiagnostic Medicine. He also serves as an assistant professor at the University of Texas at Austin Dell Medical School.
He believes that the most effective approach to neuromuscular disorders is through comprehensive diagnostic evaluation and treatment. This vision is what led Dr. Hussain to establish Austin Neuromuscular Center in 2015, one of the premier comprehensive neuromuscular centers in the nation. Most recently the National Neuromuscular Research Institute to the center as part of his continued commitment to research.
Dr. Hussain is committed to the neurology community. He has dedicated countless clinical hours to the teaching of medical students and residents from both the neurology and the physical rehabilitation and medicine departments at UT Dell Medical School. He also helped to establish “The Business of Neurology” rotation with the Texas Neurological Society to help rising physicians understand the multidimensional aspects of medical practice.
- Other Myopathies.
Hussain Y, Miller S.
Neurol Clin. 2020 Aug;38(3):619-635. doi: 10.1016/j.ncl.2020.04.002.
PMID: 32703473 Review. - Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS): Bayesian Adaptive Comparative Effectiveness Randomized Trial.
Barohn RJ, Gajewski B, Pasnoor M, Brown A, Herbelin LL, Kimminau KS, Mudaranthakam DP, Jawdat O, Dimachkie MM; Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS) Study Team, Iyadurai S, Stino A, Kissel J, Pascuzzi R, Brannagan T, Wicklund M, Ahmed A, Walk D, Smith G, Quan D, Heitzman D, Tobon A, Ladha S, Wolfe G, Pulley M, Hayat G, Li Y, Thaisetthawatkul P, Lewis R, Biliciler S, Sharma K, Salajegheh K, Trivedi J, Mallonee W, Burns T, Jacoby M, Bril V, Vu T, Ramchandren S, Bazant M, Austin S, Karam C, Hussain Y, Kutz C, Twydell P, Scelsa S, Kushlaf H, Wymer J, Hehir M, Kolb N, Ralph J, Barboi A, Verma N, Ahmed M, Memon A, Saperstein D, Lou JS, Swenson A, Cash T.
JAMA Neurol. 2021 Jan 1;78(1):68-76. doi: 10.1001/jamaneurol.2020.2590.
PMID: 32809014 Free PMC article. Clinical Trial. - Variable Presentation of Hereditary Transthyretin-Mediated Amyloidosis at a Single Center.
Hussain Y.
J Clin Neuromuscul Dis. 2021 Sep 1;23(1):7-17. doi: 10.1097/CND.0000000000000356.
PMID: 34431796 - Clinical utility of anti-cytosolic 5′-nucleotidase 1A antibody in idiopathic inflammatory myopathies.
Ikenaga C, Findlay AR, Goyal NA, Robinson S, Cauchi J, Hussain Y, Wang LH, Kershen JC, Beson BA, Wallendorf M, Bucelli RC, Mozaffar T, Pestronk A, Weihl CC.
Clin Transl Neurol. 2021 Mar;8(3):571-578. doi: 10.1002/acn3.51294. Epub 2021 Feb 8.
PMID: 33556224 Free PMC article. - Safety and efficacy of zilucoplan in patients with generalised myasthenia gravis (RAISE): a randomised, double-blind, placebo-controlled, phase 3 study.
Howard JF Jr, Bresch S, Genge A, Hewamadduma C, Hinton J, Hussain Y, Juntas-Morales R, Kaminski HJ, Maniaol A, Mantegazza R, Masuda M, Sivakumar K, Śmiłowski M, Utsugisawa K, Vu T, Weiss MD, Zajda M, Boroojerdi B, Brock M, de la Borderie G, Duda PW, Lowcock R, Vanderkelen M, Leite MI; RAISE Study Team. Lancet Neurol. 2023 May;22(5):395-406. doi: 10.1016/S1474-4422(23)00080-7. PMID: 37059508 Clinical Trial. - Zilucoplan in immune-mediated necrotising myopathy: a phase 2, randomised, double-blind, placebo-controlled, multicentre trial.
Mammen AL, Amato AA, Dimachkie MM, Chinoy H, Hussain Y, Lilleker JB, Pinal-Fernandez I, Allenbach Y, Boroojerdi B, Vanderkelen M, Delicha EM, Koendgen H, Farzaneh-Far R, Duda PW, Sayegh C, Benveniste O. Lancet Rheumatol. 2023 Feb;5(2):e67-e76. doi: 10.1016/s2665-9913(23)00003-6. Epub 2023 Jan 24. PMID: 36923454 Free PMC article. - Trial of Intravenous Immune Globulin in Dermatomyositis.
Aggarwal R, Charles-Schoeman C, Schessl J, Bata-Csörgő Z, Dimachkie MM, Griger Z, Moiseev S, Oddis C, Schiopu E, Vencovský J, Beckmann I, Clodi E, Bugrova O, Dankó K, Ernste F, Goyal NA, Heuer M, Hudson M, Hussain YM, Karam C, Magnolo N, Nelson R, Pozur N, Prystupa L, Sárdy M, Valenzuela G, van der Kooi AJ, Vu T, Worm M, Levine T; ProDERM Trial Group. N Engl J Med. 2022 Oct 6;387(14):1264-1278. doi: 10.1056/NEJMoa2117912. PMID: 36198179 Clinical Trial. - Patient preference for virtual versus in-person visits in neuromuscular clinical practice.
Hafeez K, Kushlaf H, Al-Sultani H, Joseph AC, Zaeem Z, Siddiqi Z, Laboy S, Pulley M, Habib AA, Robbins NM, Zadeh S, Hafeez MU, Hussain Y, Melendez-Zaidi A, Kassardjian C, Johnson K, Leonhard H, Biliciler S, Patino Murillas JE, Shaibani AI. Muscle Nerve. 2022 Aug;66(2):142-147. doi: 10.1002/mus.27641. Epub 2022 Jun 3. PMID: 35596667 Free PMC article.

Meet the Doctor
Shailesh Reddy, MD
Dr Shailesh Reddy received his medical degree from Michigan State University College of Human Medicine. He went on to do his residency in physical medicine and rehabilitation (PM&R) at University of Texas Dell Medical School with further specialization in neuromuscular medicine at University of California Davis.
Dr Reddy is board certified in PM&R, neuromuscular medicine, and electrodiagnostic medicine.
In addition to diagnosis and treating patients with neuromuscular disease, Dr Reddy provides trauma consults and inpatient rehabilitation services in the central Austin region. He is also an assistant professor faculty member with the PM&R residency program and spends time teaching residents in both academic and clinical settings.
Dr Reddy believes that the treatment of neuromuscular disease revolves around optimizing function through various means such as: medications, therapy, bracing etc.
Outside of clinical practice, Dr Reddy can most likely be found on the Lady bird lake trail and parks with his dog Fritz.
Journal Publications
- Reddy S., Hussain Y. “Variable Presentation and Pathologic Overlap of Rare Neuromuscular Disease.” Journal of Clinical Neuromuscular Disease: March 2019. Vol 20 (3). Abstracts
- Reddy S., Eckner JT. “Effect of Exercise on Novel Test for Clinical Reaction Time.” Medicine and Science in Sports and Exercise. 2014 March. 46 (3). 429-434
Book Chapters
- Vandenakker, C., Reddy S. “The Current State of Polio: Epidemiology and Working Towards Eradication.” Physical Medicine and Rehabilitation Clinics of North America. 2021
Manuscripts
- Reddy S., Machemehl H, Hussain Y. “Amyotrophic Lateral Sclerosis” PM&R Knowledge NOW. 20 April 2022. https://now.aapmr.org/amyotrophic-lateral-sclerosis/
- Reddy S. Hereditary and Sporadic Inclusion Body Myositis. 9 Dec 2021. https://now.aapmr.org/hereditary-and-sporadic-inclusion-body-myositis/
- Reddy S., Williams L., Tong O. “Limb Girdle Muscular Dystrophies” PM&R Knowledge NOW. 29 June 2021. https://now.aapmr.org/limb-girdle-muscular-dystrophies/
Media Mentions
- “Local Athlete with ALS to compete in London Marathon.” CBS News Austin https://cbsaustin.com/news/local/local-athlete-with-als-to-compete-in-london-marathon-austin#
- “Another path: After ALS diagnosis, Austin marathoner finishes London race in wheelchair.” Austin American-Statesman https://www.statesman.com/story/news/healthcare/2022/10/11/after-als-diagnosis-austin-marathoner-finishes-london-race-in-wheelchair/69544706007/
- “FDA Approves New ALS Drug Relyvrio, Which Aims to Slow Disease Progression” https://www.health.com/news/fda-approves-als-drug-relyvrio
Poster Presentations
- “A rare etiology of acute neuropathy” – AAPM&R Annual Meeting, 2024
- “Neurologic Immune-related Adverse Events from Immune checkpoint inhibitors: case series from single center” – AAPM&R Annual Meeting, 2024
- “Acquired Hepatocerebral Degeneration presenting with Parkinsonian-like features” – AAP Annual Meeting, 2024
- “Asymmetric Left-Hand Weakness in a Rare Case of Acute Motor Axonal Neuropathy” – AAP Annual Meeting, 2023
- “Endocrine Complications of Histone Deacetylase Inhibitor Treatment in Duchenne Muscular Dystrophy” – AANEM Annual Meeting, 2021
- “Variable Presentation and Pathologic Overlap of Hereditary Amyloidosis.” – AANEM Annual Meeting, 2019
- “Mill’s Syndrome as a Progressive Asymmetrical Limb Weakness: Case Series.” – AANEM Annual Meeting, 2019

Meet the Nurse Practitioner
Casey Kafena, MSN, AGACNP-BC
Casey Kafena is a nurse practitioner at Austin Neuromuscular Center in Austin, TX. She originally attended the University of Texas at Arlington, where she received a Bachelor of Science in Nursing. She worked for a few years in a Neuro ICU in Ft. Worth and then moved to Austin and worked for 10 more years in the general ICU. In both ICU environments, she specialized in neurologic care and took part in the acute stroke team. In 2019, she graduated from Texas Tech University with her Master of Science in Nursing and became board certified as an Adult Gerontology Acute Care Nurse Practitioner.
Casey has been working very closely with Dr. Hussain and the rest of the team in treating patients and providing compassionate care. She created and manages the ALS clinic and is involved in clinical trials, performing skin biopsies, administering botulinum toxin therapy, creating educational materials for patients and staff, and soon to be involved in pathology and autonomic test interpretation.
In her free time, she spends time with her husband, son, 2 dogs, and 1 fish! She has a love of music and comedy and may or may not be the office “prankster”. Every year there is a themed holiday card that is always a surprise.